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Tuesday, July 21 • 2:30pm - 3:00pm
W05 S02: Hierarchical Connectome Modes and Critical State Jointly Maximize Human Brain Functional Diversity

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The brain requires diverse segregated and integrated processing to perform normal functions in
terms of anatomical structure and self-organized dynamics with critical features, but the
fundamental relationships between the complex structural connectome, critical state and
functional diversity remain unknown. Herein, we extend eigenmode analysis to investigate the
joint contribution of hierarchical modular structural organization and critical state to brain
functional diversity. We show that the structural modes inherent to the hierarchical modular
structural connectome allow a nested functional segregation and integration across multiple
spatiotemporal scales. The real brain hierarchical modular organization provides large structural
capacity for diverse functional interactions, which are generated by sequentially activating and
recruiting the hierarchical connectome modes, and the critical state can best explore the
capacity to maximize the functional diversity. Our results reveal structural and dynamical
mechanisms that jointly support a balanced segregated and integrated brain processing with
diverse functional interactions, and they also shed light on dysfunctional segregation and
integration in neurodegenerative diseases and neuropsychiatric disorders.

Send your questions to our Q & A Space: https://neurostars.org/t/workshop-spatiotemporal-dynamics-in-neuroimaging-models-and-analysis-q-a/7608?u=psanzleon

avatar for Changsong Zhou

Changsong Zhou

Professor, Physics, Hong Kong Baptist University
Dr. Changsong Zhou, Professor, Department of Physics, Director of Centre for Nonlinear Studies, Hong Kong Baptist University (HKBU). Dr. Zhou’s research interest is dynamical processes on complex systems. His current emphasis is on analysis and modeling connectivity and activity... Read More →

Tuesday July 21, 2020 2:30pm - 3:00pm CEST
Crowdcast (W05)