CNS*2020 Online has ended
Welcome to the Sched instance for CNS*2020 Online! Please read the instruction document on detailed information on CNS*2020.
Back To Schedule
Sunday, July 19 • 7:00pm - 8:00pm
P83: One-shot model to learn 7 quantal parameters simoultanously, including desensitization

Log in to save this to your schedule, view media, leave feedback and see who's attending!

Feedback form is now closed.


Password : 4nf9ju

Quantal Parameters
Synapses modulate their signal to maintain stability or decrease or increase their strength. To improve quantification of synaptic dynamics with focus on computational efficiency and number of parameters, we introduce an utltra-fast variant of the binomial model, applied to estimate θ={N,p,q,σ,τd,τf,τdes}.

The supremacy of this one-shot method allows to retrieve many parameters without requiring multiple batches of training [1]. The method is suitable to spontaneous in vivo electrophysiology which makes it more general. It is the first model incorporating desensitization τdes.
We present here our last results applied to mice living in an enriched environment vs. anesthetized with trichloroethanol.

 [1] Barri A, Wang Y, Hansel D, Mongillo G. Quantifying Repetitive Transmission at Chemical Synapses: A Generative-Model Approach. eNeuro 2016, 3(2), 1-21

If you would like to write a paper together, you can contact me at myfirstname / dot / mylastname / at / imls /dot / uzh /dot / ch

avatar for Emina Ibrahimovic

Emina Ibrahimovic

University of Zurich and Elvesys
You can talk to me about the network level, the effect of a single neuron or synapse on oscillations and synchronization with Lyapunov exponents and non linear dynamics.

Sunday July 19, 2020 7:00pm - 8:00pm CEST
Slot 06